MARK: There is a new and different show debuting on CBS tonight called "Now and Again." It's an usual blend of science fiction, suspense and a little romance in there. To get a feel for the show, let's begin at the beginning. Meet the three billion dollar man, Michael Wiseman– >> MICHAEL: What size are these? >> THEO: 30 waist, 32 inseam. >> MICHAEL: Damn. >> ORDERLY: Somebody waiting to be discharged? >> THEO: Right over here. >> MICHAEL: Hey Doc, you want to see something? Take a look at this. I've never done one of these before. Never been able to. >> THEO: Mr. Wiseman. >> MICHAEL: Uh-oh. >> THEO: Mr. Wiseman. >> ORDERLY: What kind of surgery did you say you had? >> THEO: Put him down. Put him down. Put him down. MARK: Michael is played by Eric Close who's here with his co-star Margaret Colin. Good show gang. Good to see you. Eric, I'm going to start with you. You're John Goodman and you're not the $6 million man. Tell everybody what I just said and why I said that. ERIC: What happens is, the government designed a new secret weapon, and I'm bioengineered. It's a $3 billion project, which is headed up by Dr. Theodore Morris, played by Dennis Haysbert. He does a great job. The problem is, they can't design a brain. The next best thing is to salvage a brain. John Goodman's character, Michael Wiseman, who's married to this lovely lady, unfortunately gets hit by a subway train, and they grab his brain before it dies and stick it in my body. I play this regular guy who's stuck in this body but cannot make contact with his wife or daughter. MARK: Great premise. Margaret, every paper I've ever seen about this, four stars out of four, "Variety" four stars out of four. Everybody likes this. Tell me about, it's one thing having a show nobody's paying attention to. Tell me about, is there pressure for a show that has these many stars behind the reviews? MARGARET: There is always pressure. There is always some angle to work. But it's really intelligent. It's very riveting television and shot with a wonderful style. I mean, the camera work alone is a personality of show. The music is terrific. It is very romantic. It touches on every day world and also the science fiction world. Which seems to me what we're dealing with all the time, which thing in the paper will you have to incorporate into your life? MARK: One of the interesting things, you're in love with John Goodman, your husband and there was no body found, so you don't know where he is. I don't want to give away anything, might you and Eric meet because he's really your husband in a different body, down the road without giving anything away? MARGARET: I think that has to happen. How does he protect us so we don't get shot, Dennis doesn't put a bullet in my head and disrupt his wonderful new toy? But that's the wonderful yearning. That's the romantic yearning of the show. And it is fun. ERIC: There is that threat because he tells me, if you make contact with be in from your past life, they will be terminated. What do you do? He knows they're there. He can see them. He wants to with them. It's great. Glenn is good at weaving the action, the drama, the comedy and the romance altogether as one. So every week, people are going to be treated to those different elements and they won't get bored. It's just awesome. MARK: Both of you born in New York. What is it like working New York City? MARGARET: Great. You know it's great to work in New York. It's another character in the show. The city is gorgeous. It's easy to shoot here. You can disappear into a crowd and you can have your life and get home to kids. It's also insane. ERIC: Oh yeah. MARGARET: It's very glamorous in an very unexpected way to be down in the shutdown parts in the city at night at 4:00 in the morning and see Eric swinging from the buildings. ERIC: The New York Stock Exchange. It's awesome. MARGARET: You just feel like, you know, I own this town. ERIC: You have -- you can't re-create New York City. In the world, I probably think it is the most famous skyline in the world. When you see that, as a backdrop I'm climbing a building or chasing her down Lexington or whatever, and you see the Empire State Building, you can't beat that. It's just incredible. MARK: "Now and Again" tonight, 9:00. Margaret Colin and Eric Close I'm a jaded old dog and I like this. MARGARET: We got ya. MARK: Good to see both of you.